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1

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

W. Elsinghorst, Paul, Hartig, Wolfgang, Gundisch, Daniela, Mohr, Klaus, Trankle, Christian, Gutschow, Michael

Journal:

Current Topics in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

2

Editorial (Thematic Issue: Privileged Scaffolds in Natural Products and Drug Discovery)

Sun, Dianqing, Gündisch, Daniela

Journal:

Current Topics in Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 140 KB

english, 2016

3

Syntheses and evaluation of pyridazine and pyrimidine Containing bioisosteres of (±)-Pyrido[3.4-b]homotropane and Pyrido-[3.4-b]tropane as novel nAChR ligands

Daniela Gündisch, Thomas Kämpchen, Simone Schwarz, Gunther Seitz, Johanna Siegl, Thomas Wegge

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 209 KB

english, 2002

4

The twin drug approach for novel nicotinic acetylcholine receptor ligands

Tomassoli, Isabelle, Gündisch, Daniela

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 727 KB

english, 2015

5

Nicotinic acetylcholine receptor ligands as potential therapeutics

Gündisch, Daniela

Journal:

Expert Opinion on Therapeutic Patents

Year:

2005

Language:

english

File:

PDF, 273 KB

english, 2005

6

Smoking upregulates α4β2* nicotinic acetylcholine receptors in the human brain

Ullrich Wüllner, Daniela Gündisch, Hans Herzog, Martina Minnerop, Alexis Joe, Marc Warnecke, Frank Jessen, Christian Schütz, Michael Reinhardt, Wolfgang Eschner, Thomas Klockgether, Joern Schmaljohann

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 286 KB

english, 2008

7

Synthesis and Nicotinic Binding Studies on Enantiopure Diazine Analogues of the Novel (2-Chloro-5-pyridyl)-9-azabicyclo[4.2.1]non-2-ene UB-165

Gohlke, Holger, Gündisch, Daniela, Schwarz, Simone, Seitz, Gunther, Tilotta, Maria Cristina, Wegge, Thomas

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

8

Synthesis and evaluation of N1-alkylindole-3-ylalkylammonium compounds as nicotinic acetylcholine receptor ligands

Edwin G. Pérez, Bruce K. Cassels, Christoph Eibl, Daniela Gündisch

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 757 KB

english, 2012

9

Feasibility of 2–deoxy–2–[18F]fluoro–D–glucose– A85380–PET for imaging of human cardiac nicotinic acetylcholine receptors in vivo

Jan Bucerius, Alexius Y. Joe, Jörn Schmaljohann, Daniela Gündisch, Martina Minnerop, Hans-Jürgen Biersack, Ullrich Wüllner, Michael J. Reinhardt

Journal:

Clinical Research in Cardiology

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

10

Feasibility of 2–deoxy–2–[18F]fluoro–D–glucose– A85380–PET for imaging of human cardiac nicotinic acetylcholine receptors in vivo

Jan Bucerius, Alexius Y. Joe, Jörn Schmaljohann, Daniela Gündisch, Martina Minnerop, Hans-Jürgen Biersack, Ullrich Wüllner, Michael J. Reinhardt

Journal:

Clinical Research in Cardiology

Year:

2006

File:

PDF, 78 KB

2006

11

Synthesis and evaluation of phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors

Daniela Gündisch, Matthias Andrä, Lenka Munoz, Maria Cristina Tilotta

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 344 KB

english, 2004

12

Prenylated Indole Alkaloids from Flustra foliacea with Subtype Specific Binding on NAChRs

Peters, Lars, Wright, Anthony D., Kehraus, Stefan, Gündisch, Daniela, Tilotta, M. C., König, Gabriele M.

Journal:

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

13

Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors

Richard W. Fitch, Yumika Kaneko, Paul Klaperski, John W. Daly, Gunther Seitz, Daniela Gündisch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 136 KB

english, 2005

14

Syntheses and evaluation of halogenated cytisine derivatives and of bioisosteric thiocytisine as potent and selective nAChR ligands

Peter Imming, Paul Klaperski, Milton T Stubbs, Gunther Seitz, Daniela Gündisch

Journal:

European Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 251 KB

english, 2001

15

Synthesis and evaluation of diazine containing bioisosteres of (−)-ferruginine as ligands for nicotinic acetylcholine receptors

Daniela Gündisch, Klaus Harms, Simone Schwarz, Gunther Seitz, Milton T Stubbs, Thomas Wegge

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 255 KB

english, 2001

16

Effects of Aβ1−42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the τ-protein and on the α7 nicotinic acetylcholine receptor in vitro

Enzo Lain, Botond Penke, André Delacourte, Daniela Gündisch, Hannsjörg Schröder, Brigitte Witter

Journal:

European Journal of Neuroscience

Year:

2005

Language:

english

File:

PDF, 379 KB

english, 2005

17

6H,13H-Pyrazino[1,2-a;4,5-a′]diindole analogs: Probing the pharmacophore for allosteric ligands of muscarinic M2 receptors

Darius P. Zlotos, Christian Tränkle, Aliaa Abdelrahman, Daniela Gündisch, Krzysztof Radacki, Holger Braunschweig, Klaus Mohr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 228 KB

english, 2006

18

2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: Synthesis, Affinity for Nicotinic Acetylcholine Receptors, and Molecular Modeling

Koren, Andrei O., Horti, Andrew G., Mukhin, Alexey G., Gündisch, Daniela, Kimes, Alane S., Dannals, Robert F., London, Edythe D.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 158 KB

english, 1998

19

The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: The influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents

Eibl, Christoph, Tomassoli, Isabelle, Munoz, Lenka, Stokes, Clare, Papke, Roger L., Gündisch, Daniela

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

20

Nicotinic Acetylcholine Receptors and Imaging

Gundisch, Daniela

Journal:

Current Pharmaceutical Design

Year:

2000

Language:

english

File:

PDF, 89 KB

english, 2000

21

Radiodiagnostika für periphere Organerkrankungen: Nuklide und Tracer – Mechanismus und Anwendung

Daniela Gündisch

Journal:

Pharmazie in unserer Zeit

Year:

2005

Language:

german

File:

PDF, 178 KB

german, 2005

22

5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors

Mukhin, Alexey G., Gündisch, Daniela, Horti, Andrew G., Koren, Andrei O., Tamagnan, Gilles, Kimes, Alane S., Chambers, Joann, Vaupel, D. Bruce, King, Sarah L., Picciotto, Marina R., Innis, Robert B.,

Journal:

Molecular Pharmacology

Year:

2000

Language:

english

File:

PDF, 540 KB

english, 2000

23

Tetrahydrofuranylmethylamines: An efficient and simple one-step synthesis and biological activities

Marcus Limbeck, Daniela Gündisch

Journal:

Journal of Heterocyclic Chemistry

Year:

2003

Language:

english

File:

PDF, 60 KB

english, 2003

24

2-[18F]F-A-85380

Chefer, Svetlana I., Horti, Andrew G., Koren, Andrei O., Gündisch, Daniela, Links, Jonathan M., Kurian, Varughese, Dannals, Robert F., Mukhin, Alexey G., London, Edythe D.

Journal:

Year:

1999

Language:

english

File:

PDF, 496 KB

english, 1999

25

Synthesis and initial in vitro characterization of 6-[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine, a high-affinity radioligand for central nicotinic acetylcholine receptors

Andrei O. Koren, Andrew G. Horti, Alexey G. Mukhin, Daniela Gündisch, Robert F. Dannals, Edythe D. London

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2000

File:

PDF, 364 KB

2000

26

Nicotinic acetylcholine receptor ligands, a patent review (2006 – 2011)

Gündisch, Daniela, Eibl, Christoph

Journal:

Expert Opinion on Therapeutic Patents

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

27

In vitro evaluation of nicotinic acetylcholine receptors with 2-[18F]F-A85380 in Parkinson's disease

Jörn Schmaljohann, Daniela Gündisch, Martina Minnerop, Jan Bucerius, Alexius Joe, Michael Reinhardt, Stefan Guhlke, Hans-Jürgen Biersack, Ullrich Wüllner

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 481 KB

english, 2006

28

6-[18F]fluoro-A-85380, a novel radioligand for in vivo imaging of central nicotinic acetylcholine receptors

Andrew G. Horti, Svetlana I. Chefer, Alexey G. Mukhin, Andrei O. Koren, Daniela Gündisch, Jonathan M. Links, Varughese Kurian, Robert F. Dannals, Edythe D. London

Journal:

Year:

2000

Language:

english

File:

PDF, 617 KB

english, 2000

29

The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor ligands. Part 2: Carboxamide derivatives with different spacer motifs

Eibl, Christoph, Munoz, Lenka, Tomassoli, Isabelle, Stokes, Clare, Papke, Roger L., Gündisch, Daniela

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 992 KB

english, 2013

30

On the Mechanism of the Reaction of o-Benzenesulfonamido-p-benzoquinone with Ammonia and Amines

Daniela Gündisch, Karl-Artur Kovar

Journal:

Archiv der Pharmazie

Year:

1994

Language:

english

File:

PDF, 452 KB

english, 1994

31

Feasibility of [18F]-2-Fluoro-A85380-PET Imaging of Human Vascular Nicotinic Acetylcholine Receptors In Vivo

Jan Bucerius, Christoph Manka, Jörn Schmaljohann, Venkatesh Mani, Daniela Gündisch, James H.F. Rudd, Rolf Bippus, Felix M. Mottaghy, Ullrich Wüllner, Zahi A. Fayad, Hans-Jürgen Biersack

Journal:

Journal of the American College of Cardiology: Cardiovascular Imaging

Year:

2012

Language:

english

File:

PDF, 724 KB

english, 2012

32

3D QSAR Analyses-Guided Rational Design of Novel Ligands for the (α4) 2 (β2) 3 Nicotinic Acetylcholine Receptor

Gohlke, Holger, Schwarz, Simone, Gündisch, Daniela, Tilotta, Maria Cristina, Weber, Alexander, Wegge, Thomas, Seitz, Gunther

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 517 KB

english, 2003

33

In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for α4β2* nicotinic acetylcholine receptors

Daniela Gündisch, Andrei O. Koren, Andrew G. Horti, Olga A. Pavlova, Alane S. Kimes, Alexey G. Mukhin, Edythe D. London

Journal:

Year:

2005

Language:

english

File:

PDF, 117 KB

english, 2005

34

Semisynthetic Analogues of Toxiferine I and Their Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs, and the Allosteric Binding Site of Muscarinic M 2 Receptors

Zlotos, Darius P., Tränkle, Christian, Holzgrabe, Ulrike, Gündisch, Daniela, Jensen, Anders A.

Journal:

Journal of Natural Products

Year:

2014

Language:

english

File:

PDF, 434 KB

english, 2014

35

Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities

Cai, Yousheng, Sarotti, Ariel M., Gündisch, Daniela, Kondratyuk, Tamara P., Pezzuto, John M., Turkson, James, Cao, Shugeng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 418 KB

english, 2017

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